Illinois State Route 127 is the main north-south highway in Central Jackson County. It runs from the Jackson/Perry County Line to the Jackson/Union County Line. IL St Rt 127 passes through the following towns in Jackson County. Vergennes
Murphysboro
Etherton IL St Rt 127 is multi-plexed in Jackson County. Illinois State Route 13, from the Jackson/Perry County Line to Murphysboro.
EB IL St Rt 13/SB IL St Rt 127 at the Perry/Jackson County Line. EB IL St Rt 13/SB IL St Rt 127 near Dowell Road. EB IL St Rt 13/SB IL St Rt 127 near Elkville Road. EB IL St Rt 13/SB IL St Rt 127 at Vergennes. EB IL St Rt 13/SB IL St Rt 127 south of Vergennes. EB IL St Rt 13/SB IL St Rt 127 north of iL St Rt 4. EB IL St Rt 13/SB IL St Rt 127 south of IL St Rt 4. EB IL St Rt 13/SB IL St Rt 127 south of Lightfoot Road. EB IL St Rt 13/SB IL St Rt 127 near Hiser Road. EB IL St Rt 13/SB IL St Rt 127 near Industrial Park Road. EB IL St Rt 13/SB IL St Rt 127 north of IL St Rt 149. EB IL St Rt 13/SB IL St Rt 127/WB IL St Rt 149 in Murphysboro. EB IL St Rt 13/SB IL St Rt 127/WB IL St Rt 149 south of east IL St Rt 149. EB IL St Rt 13/SB IL St Rt 127/WB IL St Rt 149 near Walnut. NB IL St Rt 127/EB IL St Rt 149 west of IL St Rt 13. NB IL St Rt 127/EB IL St Rt 149 east of 5th. A green sign in Murphysboro. NB IL St Rt 127 south of Murphysboro.
