Illinois State Route 16 runs east-west across the southwestern tip of Christian County. This is the main route through the town of Pana. IL St Rt 16 passes through the following towns in Christian County. Pana
Rosamond
IL St Rt 16 is multi-plexed in Christian Cunty. U.S. Rt. 51, at Pana.
IL St Rt 16 intersect the following highways in Christian County. U.S. Rt. 51, east of Pana.
WB IL St Rt 16 at the Christian/Shelby County Line. EB IL St Rt 16 east of north U.S. Rt. 51. NB U.S. Rt. 51/EB IL St Rt 16 east of Pana. A set of junction markers on SB IL St Rt 29. A junction marker on SB IL St Rt 29. SB U.S. Rt. 51/WB IL St Rt 16 at 1st in Pana. SB U.S. Rt. 51/WB IL St Rt 16 west of Cedar in Pana. A guide marker on SB U.S. Rt. 51/WB IL St Rt 16. A junction marker on NB U.S. Rt. 51. WB IL St Rt 16 west of south U.S. Rt. 51. WB IL St Rt 16 southwest of Pana. WB IL St Rt 16 near the Christian/Montgomery County Line. EB IL St Rt 16 at the Christian/Montgomery County Line.