Illinois State Route 49 has a small portion of it run in Douglas County. Only the southbound lane of IL St Rt 49 is in Douglas County. The northbound lane is in Edgar County. IL St Rt 49 does not pass through any towns in Douglas County. IL St Rt 49 is not muli-plexed in Douglas County. IL St Rt 49 intersects the following highway in Douglas County. U.S. Rt. 36, near Newman.
SB IL St Rt 49 at the Champaign/Douglas/Edgar/Vermilion County Line. SB IL St Rt 49 near Palermo. The left lane is in Edgar County. The right lane is in Douglas County. A junction marker on SB IL St Rt 49.
