Illinois State Route 53 runs north-south through much of the northwestern tip of Cook County. This highway runs along a expressway from the Lake/Cook County Line to near the Du Page/Cook County Line. IL St Rt 53 passes through the following towns in Cook County. Elk Grove Village Schaumburg
Palatine IL St Rt 53 is multi-plexed in Cook County. Interstate 290, from Elk Grove Village to Schaumburg.