U.S. Federal Route 50 is a main east-west surface route in Lawrence County. This highway was by-passed around Lawrenceville. West of Lawrenceville the old alignment is Illinois State Route 250. In Lawrenceville, it is BUSN. U.S. Rt. 50. East of Lawrenceville to the Indiana State Line, U.S. Rt. 50 is a expressway. U.S. Rt. 50 does not pass through any towns in Lawrence County. U.S. Rt. 50 is multi-plexed in Lawrence County. Illinois State Route 250, from the Richland/Lawrence County Line to near Sumner.
U.S. Rt. 50 intersects the following highways in Lawrence County. Illinois State Route 250, near Sumner.
Branches of U.S. Rt. 50 in Lawrence County. A Lawrence County mile marker. A junction sign near Sumner. WB U.S. Rt. 50 at Bridgeport. WB U.S. Rt. 50 west of Lawrenceville. EB U.S. Rt. 50 at BUSN U.S. Rt. 50, on the westside of Lawrenceville. EB U.S. Rt. 50 at BUSN U.S. Rt. 50, on the westside of Lawrenceville. (December, 2024) East of Lawrenceville, U.S. Rt. 50 is a expressway with the speed at 65 M.P.H. WB U.S. Rt. 50 at west BUSN U.S. Rt. 50. WB U.S. Rt. 50 at the Embarras River. A guide marker on SB IL St Rt 1. A guide marker on the ramp from IL St Rt 1. A milage sign east of IL St Rt 1. A junction marker on EB BUSN U.S. Rt. 50. A guide marker on EB BUSN U.S. Rt. 50. EB U.S. Rt. 50 at May Chapel Road. EB U.S. Rt. 50 east of May Chapel Road. EB U.S. Rt. 50 at IL St Rt 33. A BGS on EB IL St Rt 33. A guide marker on EB IL St Rt 8827. WB U.S. Rt. 50 at IL St Rt 33. A junction marker on SB IL St Rt 33. A BGS on EB IL St Rt 33. A BGS on WB IL St Rt 33. EB U.S. Rt. 50 east of IL St Rt 33. A milage signs east of IL St Rt 33. WB U.S. Rt. 50 at the Illinois Welcome Sign. EB U.S. Rt. 50 at the Illinois/Indiana State Line. EB U.S. Rt. 50 at the Wabash River.