U.S. Federal Route 51 through De Witt County is a north-south grade-level expressway. This by-passes the City of Clinton, and has one spur. U.S. Rt. 51 passes through the following town in De Witt County. Wapella
U.S. Rt. 51 is not multi-plexed in De Witt County. U.S. Rt. 51 intersects the following highways in De Witt County. BUSN. U.S. Rt. 51, on the northside of Clinton.