In La Salle County, U.S. Rt. 6 is a major east-west highway. This runs about one mile north of the Illinois River and Illinois & Michigan Canal, about one mile south of Interstate 80. U.S. Rt. 6 passes through the following towns. Peru
EB U.S. Rt. 6 at the Bureau/La Salle County Line. WB U.S. Rt. 6 west of Peru. WB U.S. Rt. 6 west of Peru. (December, 2013) EB U.S. Rt. 6 in Peru. WB U.S. Rt. 6 in Downtown Peru. A BGS on NB IL St Rt 251. BGS on SB IL St Rt 251 in Peru. A BGS on SB IL St t 251. EB U.S. Rt. 6 in La Salle. A junction marker on NB IL St Rt 351. EB U.S. Rt. 6/NB IL St Rt 351 in La Salle. A set of guide markers on EB U.S. Rt. 6/NB IL St Rt 351. EB U.S. Rt. 6 west of I-39/U.S. Rt. 51. BGS on NB I-39/U.S. Rt. 51. EB U.S. Rt. 6 east of I-39/U.S. Rt. 51. EB U.S. Rt. 6 east of I-39/U.S. Rt. 51. WB U.S. Rt. 6 west of IL St Rt 178. EB U.S. Rt. 6 at IL St Rt 178. WB U.S. Rt. 6 at IL St Rt 178. EB U.S. Rt. 6 east of IL St Rt 178. EB U.S. Rt. 6 east of IL St Rt 178. (February, 2016) WB U.S. Rt. 6 near Utica. WB U.S. Rt. 6 west of Ottawa. WB U.S. Rt. 6 west of Ottawa. (March, 2014) EB U.S. Rt. 6 on the westside of Ottawa. WB U.S. Rt. 6 on the westside of Ottawa. A junction marker on SB IL St Rt 23. EB U.S. Rt. 6/IL St Rt 71, east of Columbus Street (IL St Rt 23) in Ottawa. WB U.S. Rt. 6/IL St Rt 71 east of IL St Rt 23. A junction marker on EB U.S. Rt. 6/IL St Rt 71 on the eastside of Ottawa. WB U.S. Rt. 6/IL St Rt 71 at the Fox River. WB U.S. Rt. 6/IL St Rt 71 near OSF St. Elizbeth Medical Center. WB U.S. Rt. 6/IL St Rt 71 near east U.S. Rt. 6. EB U.S. Rt. 6/IL St Rt 71 on the eastside of Ottawa. A junction marker on EB U.S. Rt. 6/NB IL St Rt 71. WB U.S. Rt. 6 east of IL St Rt 71. EB U.S. Rt. 6 east of IL St Rt 71. EB U.S. Rt. 6 east of IL St Rt 71. (February, 2014) WB U.S. Rt. 6 between Marseilles and Ottawa. WB U.S. Rt. 6 west of Marseilles. WB U.S. Rt. 6 west of Marseilles. (January, 2014) WB U.S. Rt. 6 near Bluff Street in Marseilles. WB U.S. Rt. 6 in Marseilles. EB U.S. Rt. 6 east of Marseilles. WB U.S. Rt. 6 west of Seneca. EB U.S. Rt. 6 west of IL St Rt 170. EB U.S. Rt. 6 in Seneca. A junction marker on NB IL St Rt 170. EB U.S. Rt. 6 east of Seneca. (January, 2012) EB U.S. Rt. 6 east of IL St Rt 170. (July, 2024) WB U.S. Rt. 6 near IL St Rt 170. WB U.S. Rt. 6 near Seneca. Looking west on U.S. Rt. 6 at the La Salle/Grundy County Line east of Seneca. WB U.S. Rt. 6 at the Grundy/La Salle County Line.