U.S. Federal Route 40 runs east-west across Southern Putnam County. It runs from the Clay/Putnam County Line, east of Harmony, to the Putnam/Hendricks County Line, near Stilesville. U.S. Rt. 40 passes through the following towns in Putnam County. Reelsville
Manhattan
Putnamville Mt. Meridan U.S. Rt. 40 is not multi-plexed in Putnam County. U.S. Rt. 40 intrsects the following highways in Putnam County. Indiana State Route 243, at Putnamville.
EB U.S. Rt. 40 at the Clay/Putnam County Line. EB U.S. Rt. 40 west of Reelsville. EB U.S. Rt. 40 east of Reelsville. EB U.S. Rt. 40 at Manhattan. EB U.S. Rt. 40 east of Manhattan. EB U.S. Rt. 40 west of Putnamville. A guide marker on NB IN St Rt 243. EB U.S. Rt. 40 eat of Putnamville. EB U.S. Rt. 40 at IN St Rt 75. EB U.S. Rt. 40 east of IN St Rt 75.