U.S. Federal Route 41 runs north-south in Central Warren County. From the Benton/Warren County Line to Indiana State Route 63, south of Carbondale, it is a four-lane highway. East of IN St Rt 63 it is a two-lane road to the Fountain/Warren County Line, at Attica. U.S. Rt. 41 does not pass through any towns in Warren County. U.S. Rt. 41 is multi-plexed in Warren County. Indiana State Route 26, near Rainsville. Indiana State Route 28, near Williamsport.
A junction marker on EB IN St Rt 28. SB U.S. Rt. 41/EB IN St Rt 28 near Williamsport. SB U.S. Rt. 41/IN St Rt 55; EB IN St Rt 28 near the Wabash River, west of Attica.