Iowa State Route 22 runs east-west in Northern Keokuk County. It runs from Iowa State Route 21, near Coal Creek, to the Keokuk/Washington County Line, near Kinross. IA St Rt 22 passes through the follownig towns in Keokuk County. Keswick Webster
South English
Kinross IA St Rt 22 is mutli-plexed in Keokuk County. Iowa State Route 149, from Webster to South English.
A junction marker on NB IA St Rt 149. EB IA St Rt 22/NB IA St Rt 149 east of Webster. EB IA St Rt 22/NB IA St Rt 149 west of South English. EB IA St Rt 22/NB IA St Rt 149 at north IA St Rt 14.
