Iowa State Route 78 runs east-west across the extreme southern portion of Keokuk County. It runs from the Washington/Keokuk County Line, near Richland, to Iowa State Route 149, near Martinsburg. IA St Rt 78 passes through the following town in Keokuk County. Richland
IA St Rt 78 is multi-plexed in Keokuk County. Iowa State Route 1, near Richland.
IA St Rt 78 intersects the following highways in Keokuk County. Iowa State Route 1, near Richland.
A junction marker on NB IA St Rt 1. WB IA St Rt 78 west of south IA St Rt 1. WB IA St Rt 78 at Richland. WB IA St Rt 78 west of Richland. WB IA St Rt 78 east of KCH V63. WB IA St Rt 78 near Ollie. WB IA St Rt 78 west of KCH V5G. WB IA St Rt 78 east of KCH V51. WB IA St Rt 78 west KCH V51. WB IA St Rt 78 east of IA St Rt 149. The western end of IA St Rt 78. The western end marker.
