U.S. Federal Route 34 is the main east-west highway in Central Clarke County. This runs from the Clarke/Lucas County Line, near Woodburn, to the Clarke/Union County Line, near Thayer. U.S. Rt. 34 passes through the following town in Clarke County. Osceola U.S. Rt. 34 is not multi-plexed in Clarke County. U.S. Rt. 34 intersects the following highways in Clarke County. U.S. Rt. 69, at Osceola.