U.S. Federal Route 34 is the main east-west highway in Des Moines County. This is mostly four-lanes thorugh the county. It has the only Mississippi River crossing in Des Monies County. U.S. Rt. 34 passes through the following towns in Des Moines County. Burlington West Burlington Middletown Danville U.S. Rt. 34 is multi-plexed in Des Moines County. Iowa State Route 163, through Des Moines County.
U.S. Rt. 34 intersects the following highway in Des Moines County. U.S. Rt. 61, at Burlington.
WB U.S. Rt. 34/IA St Rt 163 at the Illinois/Iowa State Line. The eastern start point of IA St Rt 163 on the Mississippi River on U.S. Rt. 34. WB U.S. Rt. 34/IA St Rt 163 crossing the Mississippi River. WB U.S. Rt. 34/IA St Rt 163 at the Iowa Welcome Sign. (October, 2011) WB U.S. Rt. 34/IA St Rt 163 at the Iowa Welcome Sign. (May, 2026) The U.S. Rt. 34/IA St Rt 163 bridge over the Mississippi River. Photo taken from the Iowa side. WB U.S. Rt. 34/IA St Rt 163 at Front Street. EB U.S. Rt. 34/IA St Rt 163 at Main Street. A BGS on EB U.S. Rt. 34/IA St Rt 163. WB U.S. Rt. 34/IA St Rt 163 at 4th Street. EB U.S. Rt. 34/IA St Rt 163 east of Curran Street. WB U.S. Rt. 34/IA St Rt 163 in Burlington. WB U.S. Rt. 34/IA St Rt 163 at Curran Street. EB U.S. Rt. 34/IA St Rt 163 at Curran Street. A junction marker on SB U.S. Rt. 61.