U.S. Federal Route 6 runs east-west in Iowa County. This runs along the southern banks of the Iowa River from the Johnson/Iowa County Line to near Marengo. U.S. Rt. 6 passes through the following towns in Iowa County. Homestead Marengo Ladora U.S. Rt. 6 is multi-plexed in Iowa County. U.S. Rt. 151, near Homestead.