U.S. Federal Route 6 runs east-west in Iowa County. This runs along the southern banks of the Iowa River from the Johnson/Iowa County Line to near Marengo. U.S. Rt. 6 passes through the following towns in Iowa County. Homestead Marengo
Ladora U.S. Rt. 6 is multi-plexed in Iowa County. U.S. Rt. 151, near Homestead.
WB U.S. Rt. 6 at the Iowa/Johnson County Line. WB U.S. Rt. 6 east of north U.S. Rt. 151. A guide marker in Eastern Iowa County. WB U.S. Rt. 6 near U.S. Rt. 151. WB U.S. Rt. 6 at north U.S. Rt. 151. WB U.S. Rt. 6/SB U.S. Rt. 151 west of Homestead. A guide marker on WB IA St Rt 220.