U.S. Federal Route 40 is an east-west highway in Douglas County. It runs along the Kansas Turnpike corridor. U.S. Rt. 40 passes through the following towns in Douglas County. Lawrence Big Springs U.S. Rt. 40 is multi-plexed in Douglas County. U.S. Rt. 24, near Lawrence. U.S. Rt. 59, at Lawrence.
U.S. Rt. 40 crosses the following highways in Douglas County. U.S. Rt. 24, at Lawrence. U.S. Rt. 59, at Lawrence.