U.S. Federal Route 73 runs mostly north-south in the center of Brown County. It runs east-west across Southeastern Brown County. U.S. Rt. 73 passes through the following towns in Brown County. Reserve Hiawatha Horton Everest U.S. Rt. 73 is multi-plexed in Brown County. U.S. Rt. 159, from the Kansas/Nebraska State Line to Horton.