Kentucky State Route 53 is a north-south highway in Central Shelby County. It runs from the Shelby/Spencer County Line, near Mt. Eden, to the Shelby/Oldham County Line, near Smithfield. KY St Rt 53 passes through the following towns in Shelby County. Mt. Eden Southville Shelbyville KY St Rt 53 is multi-plexed in Shelby County. Kentucky State Route 44, from the Shelby/Spencer County Line to Southville. U.S. Rt. 60, at Shelbyville. BUSN Kentucky State Route 55, at Shelbyville. KY St Rt 53 intersects the following highways in Shelby County. Kentucky State Route 636, at Mt. Eden. Kentucky State Route 44, at Southville. Kentucky State Route 714, at Southville. Kentucky Secondary State Route 1790, near Shelbyville. Interstate 64, at Shelbyville. Kentucky Secondary State Route 2258, at Shelbyville. U.S. Rt. 60, at Shelbyville. BUSN Kentucky State Route 55, at Shelbyville. U.S. Rt. 60, at Shelbyville. BUSN Kentucky State Route 55, at Shelbyville. Kentucky State Route 55, at Shelbyville. Kentucky State Route 362, near Shelbyville. Kentucky State Route 322, near Smithfield.