U.S. Federal Route 27 is a north-south highway in Northwestern Garrard County. It runs from the Kentucky River, at the Garrard/Jessamine County line, south of Nicholasville, to the Garrard/Lincoln County Line, south of Lancaster. U.S. Rt. 27 passes through the following towns in Garrard County. Bryantsville Lancaster
SB U.S. Rt. 27 at the Kentucky River. SB U.S. Rt. 27 on the Garrard County side of the Kentucky River. SB U.S. Rt. 27 south of KY Sec St Rt 1845. SB U.S. Rt. 27 near KY St Rt 152. SB U.S. Rt. 27 south of KY St Rt 152. A junction marker in Bryantsville. SB U.S. Rt. 27 south of KY St Rt 753. A guide marker on EB KY St Rt 52.