U.S. Federal Route 68 runs east-west across Nicholas County. This is the main surface highay across the county. U.S. Rt. 68 passes through the following town in Nicholas County. Ellisville
U.S. Rt. 68 is multi-plexed in Nicholas County. Kentucky Secondary State Route 1455, near Ellisville.
Kentucky State Route 36, near Carlisle. Kentucky State Route 648, near Carlisle. Kentucky State Route 386, near Millersburg.
Sign located in the Blue Licks Battlefield State Park. On close inspection of the sign, it is a old U.S. Rt. 62 sign. the "8" is placed over the "2". WB U.S. Rt. 68 in Rural Nicholas County.
