Maryland State Route 456 is a north-south highway in Southern Queen Anne's County. It runs near Queenstown. MD St Rt 456 passes through the following town in Queen Anne's County. Queenstown MD St Rt 456 is not multi-plexed in Queen Anne's County. MD St Rt 456 intersects the following highways in Queen Anne's County. U.S. Rt. 50, near Queenstown. Maryland State Route 656, near Queenstown. U.S. Rt. 301, near Queenstown. Maryland State Route 18, at Queenstown.