Massachusetts State Route 133 is an east-west highway in Northeastern Middlesex County. It runs from Massachusetts State Route 38/110, at Lowell, to the Essex/Middlesex County Line. MA St Rt 113 passes through the following towns in Middlesex County. Lowell North Tewksbury MA St Rt 133 is not multi-plexed in Middlesex County. MA St Rt 133 intersects the following highways in Middlesex County. Massachusetts State Route 38, at Lowell. Massachusetts State Route 110, at Lowell. Interstate 495, near North Tewksbury.
