Michigan State Route 121 runs east-west in Southwestern Kent County and Southeastern Ottawa County. It runs from Interstate 196, at Grandville, to Main Street in Zeeland. It runs north of and parallel to Interstate 196. This follows Chicago Drive. MI St Rt 121 passes through the following towns in Kent-Ottawa Counties. Grandville Jenison Hudsonville Zeeland MI St Rt 121 is not multi-plexed in Kent-Ottawa Counties. MI St Rt 121 intersects the following highways in Kent-Ottawa Counties. Interstate 196, at Grandville.