Michigan State Route 21 runs east-west in East-Central Kent County. It goes from Michigan State Route 37/44, in Grand Rapids, east to the Ionia/Kent County Line, near Lowell. MI St Rt 21 passes throught the following towns in Kent County. Grand Rapids Ada Lowell MI St Rt 21 is not multi-plexed in Kent County. MI St Rt 21 intersects the following highways in Kent County. Michigan State Route 37, at Grand Rapids. Michigan State Route 44, at Grand Rapids. Interstate 96, near Grand Rapids.