Michigan State Route 42 runs east-west across Northwestern Missaukee County. It runs from the Wexford/Missaukee County Line, east of Manton, to Michigan State Route 66, north of Lake City. MI St Rt 42 does not pass through any towns in Missaukee County. MI St Rt 42 is not multi-plexed in Missaukee County. MI St Rt 42 intersects the following highway in Missaukee County. Michigan State Route 66, near Lake City.