Michigan State Route 49 is a north-south highway in Western Hillsdale County. It runs from the Ohio/Michigan State Line, near Austin, to Michigan State Route 99, at Litchfield. MI St Rt 49 passes through the following towns in Hillsdale County. Camden
Litchfield MI St Rt 49 is multi-plexed in Hillsdale County. U.S. Rt. 12, at Allen.
MI St Rt 49 intersect the following highways in Hillsdale County. U.S. Rt. 12, at Allen.