Roads of the Mid-South & West > Highways of the State of Michigan > Michigan State Route 81
 | Michigan State Route 81 |
Michigan State Route 81 runs east-west across Eastern Michigan. It runs from Michigan State Route 13, at Saginaw, to Michigan State Route 53, near Cass City. Info on MI St Rt 81 is broken down by county below.
Saginaw County Tuscola County Sanilac County
5 March 2026