U.S. Federal Route 10 is an east-west highway in Northeastern Isabella County. It runs from the Clare/Isabella County Line, near Clare, to the Isabella/Midland County Line, near Coleman. U.S. Rt. 10 does not pass thruogh any towns in Isabella County. U.S. Rt. 10 is not multi-plexed in Isabella County. U.S. Rt. 10 intersects the following highway in Isabella County. BUSN U.S. Rt. 10, near Clare.
A junction marker on EB BUSN U.S. Rt. 10. A BGS on EB BUSN U.S. Rt. 10. EB U.S. Rt. 10 east of BUSN U.S. Rt. 10.