U.S. Federal Route 59 runs mostly north-south in Buchanan County. It runs from the Buchanan/Andrew County Line, at St. Joseph, to the Missouri/Kansas State Line, near Wintrop. U.S. Rt. 59 passes through the following towns in Buchanan County. St. Joseph Halls Rushville Winthrop U.S. Rt. 59 is multi-plexed in Buchanan County. Interstate 229, at St. Joseph. Missouri State Route 45, near Winthrop. Missouri State Route 273, near Winthrop. U.S. Rt. 59 intersects the following highways in Buchanan County. Interstate 229, at St. Joseph. Missouri State Route 759, at St. Joseph. U.S. Rt. 36, at St. Joseph.
Photo from: Paul Dienhart
Interstate 229, at St. Joseph. Missouri Secondary State Route V, at St. Joseph. Missouri State Route 752, at St. Joseph. Missouri Secondary State Route U, at St. Joseph. Missouri Secondary State Route KK, at Halls. Missouri Secondary State Route KK, near Halls. Missouri State Route 116, at Rushville. Missouri State Route 45, near Winthrop. Missouri State Route 273, near Winthrop.