U.S. Federal Route 61 runs north-south through Ste. Genevieve County. This highway provides access to the only part of the State of Illinois that is west of the Mississippi, via Missouri Secondary State Route U. While in Ste. Genevieve County it also run closely to a line of the Burlington Northern-Santa Fe railroad. U.S. Rt. 61 passes through the following towns in Ste. Genevieve County. St. Mary
Ste. Genevieve
Bloomsdale
U.S. Rt. 61 is not multi-plexed in Ste. Genevieve County. U.S. Rt. 61 intersects the following highways in Ste. Genevieve County. Missouri Secondary State Route H, at St. Mary
Missouri Secondary State Route DD, near Bloomsdale.
A junction marker on NB MO Sec St Rt H. SB U.S. Rt. 61 at MO Sec St Rt H. NB U.S. Rt. 61 at St. Mary. NB MO St Rt 61 at MO Sec St Rt U in St. Mary. NB U.S. Rt. 61 north of St. Mary. NB U.S. Rt. 61 south of Ste. Genevieve. NB U.S. Rt. 61 at MO Sec St Rt M in Ste. Genevieve. NB U.S. Rt. 61 in Ste. Genevieve. NB U.S. Rt. 61 north of Ste. Genevieve. NB U.S. Rt. 61 north of MO Sec St Rt A. NB U.S. Rt. 61 near MO Sec St Rt O. NB U.S. Rt. 61 near and old bridge south of Bloomsdale. NB U.S. Rt. 61 south of Bloomsdale.
