U.S. Federal Route 63 is a north-south expressway in Central Macon County. It runs from the Macon/Randolph County Line, near Jacksonville, to the Adair/Macon County Line, near La Plata. U.S. Rt. 63 passes through the following towns in Macon County. Macon
Axtell
La Plata
U.S. Rt. 63 is multi-plexed in Macon County. BUSN U.S. Rt. 36, at Macon. U.S. Rt. 63 intersects the following highways in Macon County. Missouri Secondary State Route T, near Excello. Missouri Secondary State Route T, near Excello. Missouri Secondary State Route YY, near Macon. Missouri Secondary State Route PP, near Macon. BUSN U.S. Rt. 36, at Macon.
SB U.S. Rt. 63 at La Plata. SB U.S. Rt. 63 south of La Plata. SB U.S. Rt. 63 near MO Sec St Rt NN. SB U.S. Rt. 63 south of Axtell. SB U.S. Rt. 63 at Macon. A BGS on EB U.S. Rt. 36. SB U.S. Rt. 63 in Macon.