New York State Route 253 runs east-west in South-Central Monroe County. It runs from New York State Route 65, near Pittsford, to New York State Route 383, at Scottsville. NY St Rt 253 passes through the following towns in Monroe County. Pittsford Henrietta NY St Rt 253 is multi-plexed in Monroe County. New York State Route 15, near Henrietta. NY St Rt 253 crosses the following highways in Monroe County. New York State Route 65, near Pittsford. New York State Route 15A, near Henrietta. Interstate 390, at Henrietta. New York State Route 15, at Henrietta. Interstate 90, (New York State Thruway) near Henrietta. New York State Route 15, near West Henrietta. New York State Route 383, at Scottsville.
A guide marker on a ramp from I-90/Thruway to I-390. A BGS on the ramp from I-90/Thruway to I-390. A guide marker on a ramp from I-90/Thruway to I-390.
