U.S. Federal Route 441 runs north-south highway in Central Macon County. It runs from the Jackson/Macon County Line, near Cowee, to the Georgia/North Carolina State Line, near Sky Valley, Georgia. U.S. Rt. 441 passes through the following towns in Macon County. East Franklin Franklin
Union Riverside Otto U.S. Rt. 441 is multi-plexed with the following highways in Macon County. U.S. Rt. 23, throughout Macon County.
Branches of U.S. Rt. 441 in Jackson County. SB U.S. Rt. 23/441; WB TRUCK U.S. Rt. 64 at the Jackson/Macon County Line. SB U.S. Rt. 23/441; WB TRUCK U.S. Rt. 64 near Cold City Lane. SB U.S. Rt. 23/441; WB TRUCK U.S. Rt. 64 near Coon Creek Road. SB U.S. Rt. 23/441; WB TRUCK U.S. Rt. 64 near Pioneer Trail. SB U.S. Rt. 23/441; WB TRUCK U.S. Rt. 64 near Brednle Road. SB U.S. Rt. 23/441; WB TRUCK U.S. Rt. 64 near Lake Emory Road. A guide marker on SB BUSN U.S. Rt. 441. SB U.S. Rt. 23/441 south of U.S. Rt. 64/BUSN U.S. Rt. 441. SB U.S. Rt. 23/441 at Addington Bridge Road. SB U.S. Rt. 23/441 near the Smokey Mountain Visitor Center. SB U.S. Rt. 23/441 north of Otto. SB U.S. Rt. 23/441 near Joe Bradley Road. SB U.S. Rt. 23/441 near Mulberry Road. SB U.S. Rt. 23/441 south of Otto. SB U.S. Rt. 23/441 north of the Georgia line. NB U.S. Rt. 23/441 at the North Carolina Welcome Sign at the Georgia/North Carolina State Line.
