Ohio State Route 16 runs east-west across Northwestern Muskingum County. It is on an expressway through Muskingum County. It runs from the Coshocton/Muskingum County Line, near Adams Mills, to the Muskingum/Licking County Line, near Black Run. OH St Rt 16 does not pass through any towns in Muskingum County. OH St Rt 16 is not multi-plexed in Muskingum County. OH St Rt 16 intersects the following highways in Muskingum County. Ohio State Route 60, near Dresden. Ohio State Route 586, near Black Run.