Pennsylvania State Route 452 is a north-south highway in Southeaster Delaware County. it runs completly within Delaware County. PA St Rt 452 passes through the following town in Delaware County. Marcus Hook PA St Rt 452 is not multi-plexed in Delaware County. PA St Rt 452 intersects the following highways in Delaware County. U.S. Rt. 13, at Marcus Hook. Interstate 95, near Marcus Hook. U.S. Rt. 322, near Marcus Hook. U.S. Rt. 1, near Chester Heights. Pennsylvania State Route 352, near Chester Heights.