Virginia State Route 106 runs east-west in the southeastern portion of the City of Petersburg. It runs from U.S. Rt. 460/BUSN U.S. Rt. 460 at the intersections of Wagner Road/Courthouse Road/Country Drive, east to the City of Petersburg/Prince George County Line, a few miles east of U.S. Rt. 460. VA St Rt 106 is not multi-plexed in the City of Petersburg. VA St Rt 106 intersects the following highways in the City of Petersburg. U.S. Rt. 460, at Petersburg. BUSN U.S. Rt. 460, at Petersburg.