U.S. Federal Route 250 runs east-west across the northern portion of the City of Richmond. It runs from the City of Richmond/Henrico County Line, near Staples Mill Road, to the eastern end point north of Downtown Richmond. U.S. Rt. 250 is multi-plexed in the City of Richmond. U.S. Rt. 33, at Richmond. U.S. Rt. 250 crosses the following highways in the City of Richmond. U.S. Rt. 33, at Richmond. Virginia State Route 197, at Richmond. Interstate 195, at Richmond. (NO Interchange) Virginia State Route 161, at Richmond. U.S. Rt. 33, at Richmond. Virginia State Route 33, at Richmond. U.S. Rt. 1, at Richmond. U.S. Rt. 301, at Richmond. Interstate 95, at Richmond. U.S. Rt. 360, at Richmond.
A guide marker on SB U.S. Rt. 1/301. EB U.S. Rt. 250 at 7th Street. EB U.S. Rt. 250 at 9th Street.
