West Virginia State Route 88 is a north-south highway in Southeastern Brooke County. It runs from the Brooke/Ohio County Line, near West Liberty, to West Virginia State Route 27, near Wellsburg. WV St Rt 88 passes through the following town in Brooke County. Bethany WV St Rt 88 is multi-plexed in Brooke County. West Virginia State Route 67, at Bethany. WV St Rt 88 intersects the following highways Brooke County. West Virginia State Route 67, at Bethany. West Virginia State Route 67, at Bethany. West Virginia State Route 27, near Wellsburg.