West Virginia State Route 88 is the main north-south highway in north-south highway in Central Ohio County. It runs from the Ohio/Marshall County Line, near Sherrard, to Ohio/Brooke County Line, near West Liberty. WB St Rt 88 passes through the following towns in Ohio County. Bethlehem Wheeling Clinton West Liberty WV St Rt 88 is multi-plexed in Ohio County. U.S. Rt. 40, at Wheeling. WV St Rt 88 crosses the following in Ohio County. U.S. Rt. 40, at Wheeling. Interstate 470, at Wheeling. (NO Interchange) Interstate 70, at Wheeling. U.S. Rt. 40, at Wheeling.