U.S. Federal Route 250 is a north-south highway in Marshall County. It runs from the Marshall/Wetzel County Line, near Littleton, to the Ohio/Marshall County Line, near Wheeling. U.S. Rt. 250 passes through the following towns in Marshall County. Cameron Limestone Moundville
Glen Dale McMechen Benwood
U.S. Rt. 250 is multi-plexed in Marshall County. West Virginia State Route 2, from Moundville to the Ohio/Marshall County Line.
A junction marker on NB WV St Rt 2. NB U.S. Rt. 250/WV St Rt 2 at 5th. NB U.S. Rt. 250/WV St Rt 2 north of 5th. NB U.S. Rt. 250/WV St Rt 2 near Walmart Dr. NB U.S. Rt. 250/WV St Rt 2 near Jefferson Ave. NB U.S. Rt. 250/WV St Rt 2 near Duck Lane. NB U.S. Rt. 250/WV St Rt 2 near 8th. NB U.S. Rt. 250/WV St Rt 2 south of Lindy Lane. NB U.S. Rt. 250/WV St Rt 2 near Zane Street. NB U.S. Rt. 250/WV St Rt 2 north og Glen Dale. NB U.S. Rt. 250/WV St Rt 2 south of Baltimore St. NB U.S. Rt. 250/WV St Rt 2 at Baltimore St. A guide marker in McMechen. A junction marker in Benwood. A BGS in Benwood. A BGS in Bendwood. NB U.S. Rt. 250/WV St Rt 2 near Marshall St. NB U.S. Rt. 250/WV St Rt 2 near 17th St. NB U.S. Rt. 250/WV St Rt 2 near South Benwood City Park. NB U.S. Rt. 250/WV St Rt 2 south of 4th St. NB U.S. Rt. 250/WV St Rt 2 at 4th St. NB U.S. Rt. 250/WV St Rt 2 north of 4th St. NB U.S. Rt. 250/WV St Rt 2 at Boggs Run Road. NB U.S. Rt. 250/WV St Rt 2 north of Boggs Run Road.