Wisconsin State Route 125 is an east-west highway in South-Central Outagamie County. It runs from Interstate 41/U.S. Rt. 41 on the westside of Appleton, to Wisconsin State Route 47, in Central Appleton. WI St Rt 125 passes through the following town in Outagamie County. Appleton
WI St Rt 125 is not multi-plexed in Outagamie County. WI St Rt 125 intersects the following highways in Outagamie County. Interstate 41, at Appleton. U.S. Rt. 41, at Appleton. Wisconsin State Route 47, at Appleton.