Wisconsin State Route 21 runs east-west along Central Monroe County. It runs from Sparta to the Monroe/Juneau County Line, near Wyeville. WI St Rt 21 passes through the following towns in Monroe County. Sparta
U.S. Rt. 12, near Tunnel City. Interstate 94, near Tunnel City. Wisconsin State Route 173, near Wyeville.
A set of guide markers on the ramp from I-94. Photo from: Paul Dienhart A set of guide markers on the ramp from WB I-90 to WI St Rt 16. EB WI St Rt 21 north of WI St Rt 16/71. A junction marker on WB WI St Rt 16/71. A junction marker on SB WI St Rt 27/EB WI St Rt 71. EB WI St Rt 16/21/71 east of WI St Rt 27. WB WI St Rt 16/21/71 at WI St Rt 27.