Wisconsin State Route 54 runs east-west across Southern Buffalo County. It goes from the Minnesota/Wisconsin State Line, near Winona, MN, to the Buffalo/Trempealeau County Line, near Marshland. WI St Rt 54 passes through the following town in Buffalo County. Bluff Siding WI St Rt 54 is multi-plexed in Buffalo County. Wisconsin State Route 35, near Bluff Siding.
WI St Rt 54 intersects the following highways in Buffalo County. Wisconsin State Route 35, at near Bluff Siding.
EB WI St Rt 54 at the Mississippi River. EB WI St Rt 54 east of the Mississippi River. EB WI St Rt 54 at north WI St Rt 35. SB WI St Rt 35/EB WI St Rt 54 south of north WI St Rt 35. SB WI St Rt 35/EB WI St Rt 54 near Bluff Siding.
