Wisconsin State Route 59 runs east-west in Southeastern Jefferson County. It runs from the Jefferson/Walworth County Line, at Whitewater, to the Jefferson/Waukesha County Line, near Eagle. WI St Rt 59 passes through the following town in Jefferson County. Palmyra
WI St Rt 59 is not multi-plexed in Jefferson County. WI St Rt 59 intersects the following highway in Jefferson County. Wisconsin State Route 106, at Palmyra.
WB WI St Rt 59 at the Jefferson/Walworth County Line. EB WI St Rt 59 east of Whitewater. EB WI St Rt 59 east of JCH D/U. EB WI St Rt 59 near Calkins Road. EB WI St Rt 59 west of Palmyra. EB WI St Rt 59 at WI St Rt 106. A guide marker on EB WI St Rt 59. EB WI St Rt 59 at Spring Lake. EB WI St Rt 59 east of Palmyra. WB WI St Rt 59 at the Jefferson/Waukesha County Line.