Roads of the Mid-South & West > Highways of the State of Wisconsin > U.S. Federal Route 53, Wisconsin > U.S. Federal Route 53; La Crosse County, Wisconsin

U.S. Federal Route 53
La Crosse County

U.S. Federal Route 53 is a north-south highway in Northwestern La Crosse County. It runs from a junction with U.S. Rt. 14/61; Wisconsin State Route 16/33 in La Crosse to the La Crosse/Trempealeau County Line, near Galesville.

U.S. Rt. 53 passes through the following towns in La Crosse County.
La Crosse
Onalaska

Holmen


U.S. Rt. 53 is multi-plexed in La Crosse County.
Wisconsin State Route 35, at La Crosse.
Interstate 90, from La Crosse to Onalaska.

Wisconsin State Route 157, at Onalaska.
Wisconsin State Route 35, from near Midway to near Trempealeau.

Wisconsin State Route 93, from near Trempealeau to the La Crosse/Trempealeau County Line.


U.S. Rt. 53 intersects the following highways in La Crosse County.
U.S. Rt. 14, at La Crosse.
U.S. Rt. 61, at La Crosse.
Wisconsin State Route 16, at La Crosse.
Wisconsin State Route 33, at La Crosse.
Wisconsin State Route 35, at La Crosse.
Interstate 90, at La Crosse.

Wisconsin State Route 35, at La Crosse.
Interstate 90, at Onalaska.
Wisconsin State Route 157, at Onalaska.
Wisconsin State Route 157, at Onalaska.
Wisconsin State Route 35, near Midway.
Wisconsin State Route 35, near Trempealeau.
Wisconsin State Route 93, near Trempealeau.


A junction marker on WB U.S. Rt. 14/NB U.S. Rt. 61.

A junction marker on WB WI St Rt 16.

A BGS on WB I-90/SB U.S. Rt. 53.

A BGS on WB I-90.

SB I-90/EB WI St Rt 157 at I-90.

SB I-90/EB WI St Rt 157 north of I-90.

A BGS on SB U.S. Rt. 53/EB WI St Rt 157.

SB U.S. Rt. 53/EB WI St Rt 157 north of I-90.

SB U.S. Rt. 53 north of WI St Rt 157.

SB U.S. Rt. 53/WI St Rt 35 north of LCCH MH.

SB U.S. Rt. 53/WI St Rt 35 south of WI St Rt 93.

SB U.S. Rt. 53/WI St Rt 93 north of WI St Rt 35.

SB U.S Rt 53/WI St Rt 93 south of LCCH T.

SB U.S. Rt. 53/WI St Rt 93 near Council Bay.

SB U.S. Rt. 53/WI St Rt 93 at the La Crosse/Trempealeau County Line.

14 June 2022