Interstate 64, Illinois
Roads of the Mid-South & West > Highways of the State of Illinois > Interstate 64, Illinois

Interstate 64

Interstate 64 runs east-west across southern Illinois. It follows the Illinois State Route 15 corridor. It connects St. Louis to Mt. Veronon and Evansville, via Interstate 164 in Indiana.

I-64 is multi-plexed in Illinois.

I-64 is multi-plexed with...

...Interstate 55, at East St. Louis.
...U.S. Rt. 40, at East St. Louis.

...Illinois State Route 3, for aprox. 1 mile at the Illinois/Missouri State Line.

...U.S. Rt. 50, from Caseyville to O'Fallon.

...Interstate 57, at Mt. Vernon.


While in Illinois, Interstate 64 crosses the following interstate.

Interstate 55, at East, St. Louis.
Interstate 70, at East St. Louis.

The first BGS for the split of I-55/70 and I-64.

Another BGS on NB I-55; EB I-64/70.

NB I-55; EB I-70 at the split of EB I-64 in East St. Louis.

NB I-55; EB I-64/U.S. Rt. 40 near their split. (July, 2016)

NB I-55; EB I-64/U.S. Rt. 40 at their split. (July, 2016)

WB I-64 over one mile fron I-55/70.

The one mile BGS on WB I-64.

WB I-64 near I-55/70.

Lane markers on WB I-64 near I-55/70.

WB I-64 at I-55/70.

WB I-64 over one mile from I-55/70. (July, 2014)

WB I-64 near I-55/70. (July, 2014)

WB I-64 before I-55/70. (July, 2014)

WB I-64 at I-55/70. (July, 2014)

Interstate 255, at Caseyville.

A BGS on WB I-64.

WB I-64 near I-255.

WB I-64 at I-255.

WB I-64 at I-255. (July, 2014)

EB I-64 two miles from I-255.

EB I-64 one mile from I-255.

A BGS on EB I-64.

EB I-64 at I-255.
Interstate 57, at Mt. Vernon.

EB I-64 two miles from I-57.

EB I-64 one mile from I-57.

EB I-64 near I-57.

EB I-64 at I-57.

The first BGS on NB I-57/WB I-64.

A graphical BGS on NB I-57/WB I-64.

NB I-57/WB I-64 at thier split on the northside of Mt. Vernon.
Interstate 57, at Mt. Vernon.

A BGS one mile from the split of SB I-57/EB I-64.

Another graphical BGS on SB I-57/I-64.

SB I-57/EB I-64 at their split on the southside of Mt. Vernon.


There are not branches of I-64 in Illinois.


NB I-55; EB I-64/U.S. Rt. 40 at the IL/MO State Line.

NB I-55; EB I-64/U.S. Rt. 40 at the Illinois State Line.

Overhead signage just over the Illinois State Line at the Poplar Street Bridge, St. Louis, MO.

SB I-55; WB I-64/U.S. Rt. 40 as seen from the Union Pacific railroad overpass in the photo above.

A junction marker on NB IL St Rt 3.

A set of BGS's on NB IL St Rt 3.

Loking north along I-55/64; U.S. 40; IL in East St. Louis. Photo from SB I-55/IL St Rt 3; WB I-64/U.S. 40 to Tudor Ave.

NB I-55/IL St Rt 3; EB I-64/EB U.S. Rt. 40 at the Illinois Welcome Sign. (September, 2007)

A BGS on SB I-55/IL St Rt 3; WB I-64/U.S. Rt. 40.

A road work advisory sign on NB I-55; EB I-64/U.S. Rt. 40.

SB I-55/IL St Rt 3; WB I-64/U.S. Rt. 40 near the King Bridge exit in East St. Louis.

WB I-64/U.S. Rt. 40; SB I-55/IL St Rt 3 near 3rd Street in East St. Louis.

A set of guide markers on SB IL St Rt 3.

A BGS on NB IL St Rt 3.

EB I-64 near 15th Street in East St. Louis.

A BGS along I-64 in East St. Louis. The unique thing about this sign is that I-64 does not go to Salem.

A BGS on NB IL St Rt 111.

WB I-64 west of I-255/U.S. Rt. 50.

WB I-64 west of I-255/U.S. Rt. 50.

A guide marker on WB I-64.

Guide sign on SB I-255.

A BGS on WB I-64/U.S. Rt. 50.

EB I-64/U.S. Rt. 50 near IL St Rt 157 in Caseyville.

A junction marker on NB IL St Rt 157.

A BGS on SB IL St Rt 157.

A set of guide markers in Fairview Heights.

WB I-64/U.S. Rt. 50 west of IL St Rt 159.

A BGS on Old U.S. Rt. 50 in O'Fallon.

A mile marker on WB I-64.

A BGS on NB IL St Rt 158.

A guide marker on SB IL St Rt 4.

A set of guide markers on SB IL St Rt 4.

EB I-64 east of Illinois State Route 4.

A BGS on EB IL St Rt 161.

A junction marker on SB U.S. Rt. 51.

EB I-64 near Woodlawn.

A guide sign on SB IL St Rt 37 in Mt. Vernon.

A junction marker on EB IL St Rt 15 in Mt. Vernon.

A BGS on WB IL St Rt 15.

A BGS on WB IL St Rt 15.

A guide sign on NB I-57, north of I-24.

WB I-64 east of IL St Rt 242.

WB I-64 near Aden.

A set of guide markers on NB IL St Rt 1.

A BGS on NB IL St Rt 1.

EB I-64 near Grayville.

WB I-64 at the Illinois/Indiana State Line.

19 November 2014