Interstate 64 runs east-west across southern Illinois. It follows the Illinois State Route 15 corridor. It connects St. Louis to Mt. Veronon and Evansville, via Interstate 164 in Indiana. I-64 is multi-plexed in Illinois.
The first BGS for the split of I-55/70 and I-64. Another BGS on NB I-55; EB I-64/70. NB I-55; EB I-70 at the split of EB I-64 in East St. Louis. WB I-64 over one mile fron I-55/70. The one mile BGS on WB I-64. WB I-64 near I-55/70. Lane markers on WB I-64 near I-55/70. WB I-64 at I-55/70.
A BGS one mile from the split of SB I-57/EB I-64. Another graphical BGS on SB I-57/I-64. SB I-57/EB I-64 at their split on the southside of Mt. Vernon. There are not branches of I-64 in Illinois. NB I-55; EB I-64/70; U.S. Rt. 40 at the IL/MO State Line. Overhead signage just over the Illinois State Line at the Poplar Street Bridge, St. Louis, MO. SB I-55; WB I-64/70-U.S. Rt. 40 as seen from the Union Pacific railroad overpass in the photo above. A junction marker on NB IL St Rt 3. A set of BGS's on NB IL St Rt 3. Loking north along I-55/64/70; U.S. 40; IL in East St. Louis. Photo from SB I-55/IL St Rt 3; WB I-64/70-U.S. 40 to Tudor Ave. NB I-55/IL St Rt 3; EB I-64/70; EB U.S. Rt. 40 at the Illinois Welcome Sign. (September, 2007) A road work advisory sign on NB I-55; EB I-64/70-U.S. Rt. 50. A set of guide markers on SB IL St Rt 3. EB I-64 near 15th Street in East St. Louis. A BGS along I-64 in East St. Louis. The unique thing about this sign is that I-64 does not go to Salem. A BGS on NB IL St Rt 111. A guide marker on WB I-64. Guide sign on SB I-255. EB I-64/U.S. Rt. 50 near IL St Rt 157 in Caseyville. A BGS on Old U.S. Rt. 50 in O'Fallon. A mile marker on WB I-64. A BGS on NB IL St Rt 158. EB I-64 east of Illinois State Route 4. A BGS on EB IL St Rt 161. A guide sign on SB IL St Rt 37 in Mt. Vernon. A junction marker on EB IL St Rt 15 in Mt. Vernon. A BGS on WB IL St Rt 15. A guide sign on NB I-57, north of I-24. WB I-64 east of IL St Rt 242. WB I-64 near Aden. A set of guide markers on NB IL St Rt 1. A BGS on NB IL St Rt 1. EB I-64 near Grayville. WB I-64 at the Illinois/Indiana State Line.
