Illinois State Route 100 runs north-south through Northwestern Scott County. This is one of the main surface highways of the county. IL St Rt 100 passes through the following town in Scott County. Bluffs IL St Rt 100 is multi-plexed in Scott County. Illinois State Route 106, from the Pike/Scott County Line to near Florence.
IL St Rt 100 intersects the following highways in Scott County. Illinois State Route 106, near Florence.
SB IL St Rt 100/WB IL St Rt 106 near the Illinois River. SB IL St Rt 100/WB IL St Rt 106 at the first warning sign for the draw bridge. A junction marker on WB IL St Rt 106. A mileage chart north of IL St Rt 106. A Scott County mile marker. NB IL St Rt 100 in Rural Scott County. NB IL St Rt 100 at I-72/U.S. Rt. 36. A NB guide marker. A BGS on WB I-72/U.S. Rt. 36. A BGS on EB I-72/U.S. Rt. 36.
