Illinois State Route 121 is one of the main highways in Cumberland County. This connects the county seat, Toledo, to Effingham. IL St Rt 121 passes through the following towns in Cumberland County. Toledo
Greenup
IL St Rt 121 is multi-plexed in Cumberland County. U.S. Rt. 45, near Trilla. IL St Rt 121 crosses the following highways in Cumberland County. U.S. Rt. 45, near Trilla. Interstate 70, near Greenup. (NO INTERCHANGE) Illinois State Route 130, at Greenup.
EB IL St Rt 121 east of Toledo. The eastern end point in Greenup. The eastern end marker.
