Illinois State Route 145 runs north-south in Central Massac County. It runs from U.S. Rt. 45, near Metropolis, to the Massic/Pope County Line. IL St Rt 145 does not pass through the following towns in Massac County. IL St Rt 145 is not multi-plexed in Massac County. IL St Rt 145 intersects the following highways in Massac County. U.S. Rt. 45, near Metropolis.