Illinois State Route 164 is a short east-west highway in West-Central Knox County. It runs from the Knox/Warren County Line to U.S. Rt. 34/Illinois State Route 41, at Galesburg. IL St Rt 164 passes through the following town in Knox County. Galesburg
IL St Rt 164 is not multi-plexed in Knox County. IL St Rt 164 intersects the following highways in Knox County. U.S. Rt. 34, at Galesburg. Illinois State Route 41, at Galesburg.