Illinois State Route 48 runs north-south in Northwestern Piatt County. Only the northbound lane of IL St Rt 48 is in Piatt County. This is from the Macon/Piatt County Line, near Cisco, to the De Witt/Piatt County Line, near Weldon. IL St Rt 48 does not pass through any towns in Piatt County. IL St Rt 48 is not multi-plexed in Piatt County. IL St Rt 48 intersects the following highways in Piatt County. Illinois State Route 32, near Cisco.
